April 2013

Introduction

CT Perfusion in Nonsurgical Organ Preservation Therapy

Suresh Mukherji

Suresh Mukherji

CT perfusion provides the unique ability to noninvasively quantify the microvascular blood flow of tumors and normal tissues. CTP provides important information on the biologic response to nonsurgical organ preservation and has the potential to determine whether the tumor is properly responding to nonsurgical organ preservation therapy (NSOPT). The ability to noninvasively monitor … more »

Head & Neck

Perfusion CT in Squamous Cell Carcinoma

Sotirios Bisdas

Sotirios Bisdas

Malignancies in the head and neck and their nodal involvement often present in an advanced stage that reduces the chances for successful treatment and prolonged survival rates. Though clinical endoscopic examination is the cornerstone of therapeutic strategies, follow-up is hampered by unspecific tissue changes, whereas the response on the increasingly used neo-adjuvant therapy … more »

Head & Neck

Correlation between Initial and Early Follow-Up CT Perfusion Parameters with Endoscopic Tumor Response in Patients with Advanced Squamous Cell Carcinomas of the Oropharynx Treated with Organ-Preservation Therapy

Dheeraj Gandhi

Dheeraj Gandhi

Recent advances in anatomic imaging techniques have significantly improved our ability to assess the locoregional spread of head and neck cancers. While CT and MR imaging remain the gold standard for radiographic evaluation in mapping the extent of primary tumor and regional metastasis, early and accurate detection of tumor recurrence, as well as … more »

Head & Neck

Can Pretreatment CT Perfusion Predict Response of Advanced Squamous Cell Carcinoma of the Upper Aerodigestive Tract Treated with Induction Chemotherapy?

Aaron Zima

Aaron Zima

Traditional radiology has focused on the anatomic description of disease before and after therapy. While this is vital to the overall care of patients, as health care moves forward, there will be more and more emphasis placed upon cost containment and patient outcomes for administered therapies. Predicting whether a certain disease process will … more »