July 2013

Introduction

Deep Brain Stimulation and Neuroradiology

Falgun Chokshi

Falgun Chokshi

The idea of using long, sharp metallic instruments to enter the anterior cranium and frontal lobes to “treat” certain disorders conjures up images of the infamous frontal lobotomies performed in Europe and the United States from the 1930s to 1950s. Over the last decade, however, metallic … more »

Brain

Neuroimaging and Deep Brain Stimulation

Didier Dormont

Didier Dormont

Deep brain stimulation (DBS) was initially employed to cure intractable tremor in the early 1990s1 by A. Benabid, a French mathematician and stereotactic neurosurgeon who, at that time, described  bilateral subthalamic nucleus DBS for advanced Parkinson disease (PD).2 Coubes in Montpellier3 utilized chronic bilateral stimulation of … more »

Brain

Automated Optimization of Subcortical Cerebral MR Imaging−Atlas Coregistration for Improved Postoperative Electrode Localization in Deep Brain Stimulation

Thomas Schönecker

Thomas Schönecker

This article features a specific method that points to the important question of increasing the anatomic accuracy in localizing electrode contacts in deep brain stimulation (DBS) of the basal ganglia. Representing my primary research interest, electrode localization appears to play a significant role, first in quantitative … more »

Functional

Functional Connectivity Targeting for Deep Brain Stimulation in Essential Tremor

Jeffrey Anderson

Jeffrey Anderson

Functional neurosurgery is a rapidly emerging tool to treat dozens of neuropsychiatric and neurologic conditions. Yet, one of the biggest limitations of deep brain stimulator placement, high-frequency ultrasound ablations, and cortical stimulator treatments is identifying the correct target for therapy. I see image guidance for such … more »