March 2014

Introduction

Mild Traumatic Brain Injury

Saeed Fakhran

Saeed Fakhran

The imaging of mild traumatic brain injury (MTBI), commonly referred to as concussion, is a maturing and expanding field, with novel imaging methods being used for both clinical evaluation of patients as well as in research. While initial concussion imaging was focused on excluding more serious pathology (eg, hemorrhage) in these patients, the … more »

Functional

Extent of Microstructural White Matter Injury in Postconcussive Syndrome Correlates with Impaired Cognitive Reaction Time: A 3T Diffusion Tensor Imaging Study of Mild Traumatic Brain Injury

Pratik Mukherjee

Pratik Mukherjee

Bruce McCandliss

Bruce McCandliss

DTI characterizes the microstructural properties of biologic tissues through measurements of the orientation-dependent diffusivity of water protons. This renders DTI particularly sensitive to human brain white matter pathology at microscopic spatial scales, because the longitudinal arrangement of the axolemma, microtubules, neurofilaments, and myelin … more »

Brain

Proton MR Spectroscopy and MRI-Volumetry in Mild Traumatic Brain Injury

Oded Gonen

Oded Gonen

Traumatic brain injury (TBI) annually accounts for 1.6 million emergency department visits and hospitalizations in the United States.1 More than 85% of TBIs are classified as “mild” (MTBI), whose radiologic findings are minimal, if any, and do not correspond to clinical symptoms; consequently, it is suspected that many more victims do not seek medical … more »

Brain

Decreased Fractional Anisotropy Evaluated Using Tract-Based Spatial Statistics and Correlated with Cognitive Dysfunction in Patients with Mild Traumatic Brain Injury in the Chronic Stage

Tetsuya Wada

Tetsuya Wada

Yoshitaka Asano

Yoshitaka Asano

Approximately 80% of nonfatal traumatic brain injuries (TBIs) are classified as mild. Although they occur often, the pathophysiological, neurophysiological, and neuropsychological mechanisms of mild TBI (MTBI) remain poorly understood. Clinically, TBI is associated with the cognitive disturbances that often cause problems in family, … more »