August 2014

Introduction

Brain Atrophy in Multiple Sclerosis

Alex Rovira

Alex Rovira

Multiple sclerosis (MS) is a chronic, persistent inflammatory-demyelinating disease of the central nervous system (CNS), characterized pathologically by areas of inflammation, demyelination, axonal loss, and gliosis scattered throughout the CNS. The disease has a predilection for the optic nerves, brain stem, spinal … more »

Brain

Automated Determination of Brain Parenchymal Fraction in Multiple Sclerosis

Mattias Vågberg

Mattias Vågberg

The importance of brain atrophy in neurodegenerative disorders is well-known. Considering the example of multiple sclerosis (MS), brain atrophy has been shown to be a valuable biomarker both for prognostic considerations and for measuring treatment effect. Although determination of brain atrophy is … more »