December 2014

Introduction

Computational Fluid Dynamics

Charles M. Strother

Charles M. Strother

Over the last several years the number of reports related to computational fluid dynamics (CFD) in the AJNR has increased significantly. A majority concerned intracranial aneurysms (IAs), with the primary focus being on development and validations of a technique that could allow clinically useful predictions of IA risk of rupture. Although several papers on … more »

Interventional

Patient-Specific Computational Hemodynamics of Intracranial Aneurysms from 3D Rotational Angiography and CT Angiography: An In Vivo Reproducibility Study

Arjan Geers

Arjan Geers

Over the last decade, computational modeling of hemodynamics in cerebral aneurysms has grown tremendously as a field of research. The expectation is that one day patient-specific hemodynamic data will complement the currently available information and improve clinical decision-making. Although in vivo techniques that measure hemodynamic quantities are getting better, computational modeling provides superior temporal and … more »

Interventional

Generalized versus Patient-Specific Inflow Boundary Conditions in Computational Fluid Dynamics Simulations of Cerebral Aneurysmal Hemodynamics

Ivo Jansen

Ivo Jansen

Clinical decisions regarding preventive treatment of unruptured aneurysms are not straightforward. Often, the question arises if risk of rupture outweighs risk of treatment. In these cases, rupture risk is currently assessed mainly based on size, location, and growth of the aneurysm. Although it has been shown that these parameters influence risk of rupture, they do not … more »

Interventional

Quantifying the Large-Scale Hemodynamics of Intracranial Aneurysms

Greg Byrne

Greg Byrne

Computational fluid dynamic simulations using patient-specific vascular geometries provide a powerful tool for understanding, treating, and preventing a variety of cerebrovascular diseases. The underlying goal of our research is to use such patient-specific modeling to connect hemodynamic variables with clinical events, thereby gaining a better understanding of intracranial aneurysm development and the mechanisms that may … more »

Interventional

Intracranial Aneurysm Neck Size Overestimation with 3D Rotational Angiography: The Impact on Intra-Aneurysmal Hemodynamics Simulated with Computational Fluid Dynamics

Joppe Schneiders

Joppe Schneiders

Aneurysm rupture risk is incredibly difficult to predict. Many risk factors have been identified already, but the impact of hemodynamics on aneurysm rupture risk remains unclear. Computational fluid dynamics (CFD) is a virtual technique that enables researchers to simulate blood flow patterns in vessels, and even in small intracranial aneurysms. In the field of CFD, … more »

Interventional

Mind the Gap: Impact of Computational Fluid Dynamics Solution Strategy on Prediction of Intracranial Aneurysm Hemodynamics and Rupture Status Indicators

Kristian Valen-Sendstad

Kristian Valen-Sendstad

Computational fluid dynamics (CFD) is increasingly relied upon for elucidating blood flow dynamics in cerebral aneurysms and their possible role in determining rupture risk. Compared with a decade ago, when “patient-specific” aneurysm CFD studies were confined to a few specialized labs, often using their own in-house solvers, today the use of CFD in aneurysm research … more »