January 2015

Brain

White Matter Alteration of the Cingulum in Parkinson Disease with and without Dementia: Evaluation by Diffusion Tensor Tract–Specific Analysis

Koji Kamagata

Koji Kamagata

Parkinson disease (PD) is the second most frequent neurodegenerative disorder after Alzheimer disease.1 In PD, the primary pathologic changes involve loss of nigrostriatal dopaminergic neurons and the presence of Lewy bodies (α-synuclein–immunoreactive inclusions), with neuronal loss in numerous brain regions.2 To distinguish … more »

Brain

Thalamic Projection Fiber Integrity in de novo Parkinson Disease

David E. Vaillancourt

David E. Vaillancourt

My lab is dedicated to understanding Parkinson disease (PD) and movement disorders, to improve patient care in the future. MRI has tremendous potential to provide improved diagnostics and tracking of PD progression, and we are committed to this endeavor.

The current … more »