February 2015

Introduction

PET-CT Imaging in Head and Neck Cancer

Saeed Fakhran

Saeed Fakhran

Carcinoma of the squamous lining of the mucosal surfaces of the head and neck, collectively known as head and neck cancer, accounts for over 50,000 cases per year and represents approximately 3% of all cancers in the United States. Traditionally, head and neck cancer was thought to be a disease of older people … more »

Head & Neck

Using FDG-PET to Measure Early Treatment Response in Head and Neck Squamous Cell Carcinoma: Quantifying Intrinsic Variability in Order to Understand Treatment-Induced Change

Jenny Hoang

Jenny Hoang

The study was performed because we saw that clinicians were turning toward PET to provide information on early treatment or “intratreatment” response in head and neck squamous cell cancer (HNSCC). They saw an opportunity for intratreatment PET to detect favorable or unfavorable metabolic changes early in treatment and help to determine whether a … more »

Head & Neck

Negative Predictive Value of Surveillance PET/CT in Head and Neck Squamous Cell Cancer

Marion Hughes

Marion Hughes

The optimal utilization of PET/CT imaging in patients with head and neck squamous cell cancer (HNSCC) is a topic of immediate concern for radiology. Payers are restricting access to this modality without any data to support their decisions. It is critical for radiologists to supply the data upon which intelligent utilization decisions can … more »

Head & Neck

Osteoradionecrosis after Radiation Therapy for Head and Neck Cancer: Differentiation from Recurrent Disease with CT and PET/CT Imaging

Lea Alhilali

Lea Alhilali

Squamous cell carcinoma of the head and neck accounts for over 550,000 cases annually worldwide. Primary risk factors include tobacco use, alcohol consumption, and infection with human papillomavirus (HPV) (for oropharyngeal cancer) and Epstein-Barr virus (for nasopharyngeal cancer). Among the primary treatment modalities for this disease is chemoradiotherapy, either in isolation or following … more »

Review Article

Biologic Imaging of Head and Neck Cancer: The Present and the Future

Ashok Srinivasan

Ashok Srinivasan

We are transitioning into an era where personalized medicine, in terms of individualized treatment options, will play a pivotal role in the management of head and neck cancer. It has been recognized for some time that anatomic imaging (conventional CT and MRI) has its limitations in characterizing the functional or physiologic status of … more »