September-October 2015

Introduction

Clinical Applications of Arterial Spin-Labeling

Guest Editor Karl-Olof Lovblad

Guest Editor Karl-Olof Lövblad

Arterial spin-labeling (ASL) is a technique that has been around for a number of years but which remained dormant until recent enthusiasm developed again about its use and, finally, acceptance came over the last few years. From the start it was, … more »

Pediatrics

Arterial Spin-Labeled Perfusion of Pediatric Brain Tumors

Kristen W. Yeom

Kristen W. Yeom

Brain tumors are the most common solid neoplasm of childhood and also a leading cause of cancer deaths in children. Unfortunately, these pediatric tumors can look bizarre, with a buffet of pathology that can be quite daunting when we first encounter them. For example, … more »

Brain

Quantitative Blood Flow Measurements in Gliomas Using Arterial Spin-Labeling at 3T: Intermodality Agreement and Inter- and Intraobserver Reproducibility Study

Toshinori Hirai

Toshinori Hirai

Perfusion MR imaging with arterial spin-labeling (ASL) is a method using magnetically labeled blood water protons as an endogenous tracer to allow visualization and measurement of perfusion. Over the last decade, this technique has been used to evaluate perfusion in various pathologic conditions. The usefulness of perfusion MR … more »

Pediatrics

Hydrocephalus Decreases Arterial Spin-Labeled Cerebral Perfusion

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Kristen W. Yeom

Hydrocephalus is a common neurosurgical condition that often requires radiologist input. Some cases are pretty straightforward. For example, a patient comes in with headaches or altered mental status with newly enlarged vents, periventricular edema, and has hemorrhage or a big tumor causing obstruction. Or, there might … more »

Pediatrics

Quantitative Cerebral Perfusion Imaging in Children and Young Adults with Moyamoya Disease: Comparison of Arterial Spin-Labeling–MRI and H2[15O]-PET

Robert Goetti

Robert Goetti

In children with Moyamoya disease, cerebral perfusion studies are essential for preoperative planning and postoperative follow-up after revascularization procedures. As these children often undergo repeat examinations, the potential cumulative radiation burden of nuclear medicine studies, DSA, and CT is considerable and should be minimized as far … more »