November-December 2015

Introduction

IgG4-Related Disease

Guest Editor Julie Bykowski, MD

Guest EditorJulie Bykowski, MD

The multisystem involvement of IgG4-related disease (IgG4-RD) has been identified only within the past 15 years,1,2 over a century since Mikulicz’s report3 of a man with swelling of the lacrimal, submandibular, and parotid glands. Pancreatitis and sialadenitis are the 2 most common … more »

Head & Neck

MR Imaging of IgG4-Related Disease in the Head and Neck and Brain

Keiko Toyoda, MD

Keiko Toyoda, MD

The concept of IgG4-related disease (IgG4-RD) was first proposed by Hamano1 in 2001, and Japanese investigators have subsequently continued to play a leading role in defining its clinical spectrum and diagnostic criteria. In 2001 and 2002, Hamano et al1,2 reported autoimmune pancreatitis (AIP) associated … more »

Head & Neck

Orbital Lymphoproliferative Disorders (OLPDs): Value of MR Imaging for Differentiating Orbital Lymphoma from Benign OPLDs

Kyoko Haradome, MD

Kyoko Haradome, MD

Orbital lymphoproliferative disorders (OLPDs) frequently appear as an orbital mass lesion (24–49%) and comprise a wide spectrum of diseases ranging from benign to malignant conditions. The majority of malignant OLPDs are orbital lymphomas, particularly mucosa-associated lymphoid tissue (MALT) lymphoma. Other OLPDs comprise several benign, … more »