November-December 2017

Introduction

MR Imaging Genomics and Medulloblastoma

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Marlene Baumann

Radiogenomics, or imaging genomics, is a term that describes an exciting emerging field of research that is aimed at defining relationships between image features (image phenotypes) and molecular markers (molecular phenotypes).1  Traditionally, radiology has been primarily focused on the correlation between imaging and histopathologic findings.  

Merging the fields of standard imaging and … more »

Expedited Publication

MRI Surrogates for Molecular Subgroups of Medulloblastoma

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Kristen Yeom

Back in February 2008, Scott Atlas, Paul Fisher, and I sat together brainstorming how we might tackle tricky cases of patients with pediatric medulloblastomas. This was a time before molecular subtyping of medulloblastoma. We all knew medulloblastomas could look like anything. They could sit in intra- and/or extra-axial spaces. They could look … more »

Pediatrics

MR Imaging Characteristics of Wingless-Type – Subgroup Pediatric Medulloblastoma

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Zoltan Patay

Imaging genomics is one of the new “hot topics” and “buzzwords” in diagnostic imaging alongside radiomics, computer-aided diagnosis, and deep learning and artificial intelligence. We wanted to test if a very simple, location-based approach would shed new light on the cellular origins of molecular medulloblastoma groups and validate some of the recent … more »