May-June 2017
Head & Neck

Visualization of the Peripheral Branches of the Mandibular Division of the Trigeminal Nerve on 3D Double-Echo Steady-State with Water Excitation Sequence

Fujii pic

Hiroyuki Fujii

Cranial nerve impairments can significantly compromise functionality and quality of life. Knowledge of the anatomic course of each cranial nerve and its relationship with surrounding structures is important for diagnosing various cranial pathologies and preventing complications from surgical interventions.

Despite recent advances in MR imaging technology, visualization of the entire course of the cranial nerves, especially the extracranial segments, remains challenging in routine clinical practice. A 3D double-echo steady-state with water excitation (3D-DESS-WE) sequence, commonly used in the orthopedic field, was recently applied to visualize the intraparotid facial nerve with a 1.5T MR unit and was quite successful.1 We have applied this technique to the trigeminal nerve with a 3T MR unit to investigate the detectability of the extracranial peripheral branches of the mandibular nerve (V3) because the trigeminal nerve has the largest distribution of innervation among all the cranial nerves in the suprahyoid neck, and the V3 is the largest division of the trigeminal nerve.2

The 3D-DESS-WE sequence involves the acquisition of 2 different echoes during each TR based on the steady-state free precession technique. The first echo is the free induction decay gradient echo used in the FISP sequence and the second is the spin-echo used in the reversed fast imaging with steady-state free precession (PSIF) sequence. PSIF signal intensity has a dominant T2 contrast.3 The FISP signal intensity provides more anatomic details with tissue contrast dominated by the T1/T2 ratio.1 With the signal characteristics, the 3D-DESS-WE sequence shows the nerve itself as a high-signal-intensity structure.

There are 3 advantages to using the 3D-DESS-WE sequence for MR neurography: 1) it has a relatively short acquisition time, 2) it can be imaged using a standard, commercially available head/neck coil without a surface coil, and 3) it enables uniform detectability of the peripheral branches of the cranial nerve by readers at various training levels.2 These features make the 3D-DESS-WE sequence feasible in routine clinical practice. Currently, because the surgeons at our institution highly praise this novel MR neurography technique, we routinely run the 3D-DESS-WE sequence to demonstrate the relationship between cranial nerves and lesions and to help our head and neck/oral surgeons plan treatment.

We presented an abstract on the usefulness of imaging the intraparotid facial nerve for preoperative parotid tumors at RSNA 2016.4

We hope to continue investigating the potential of the 3D-DESS-WE sequence for visualizing the extracranial segments of other cranial nerves and for diagnosing cranial nerve pathologies such as perineural spread of malignancy and infectious/inflammatory disease. Because the 3D-DESS-WE sequence can detect abnormalities without contrast media, it can be applied to patients with renal failure.

References

  1. Qin Y, Zhang J, Li P, et al. 3D double-echo steady-state with water excitation MR imaging of the intraparotid facial nerve at 1.5 T: a pilot study.. AJNR Am J Neuroradiol 2011;32:1167–72, 10.3174/ajnr.A2480
  2. Fujii H, Fujita A, Yang A, et al. Visualization of the peripheral branches of the mandibular division of the trigeminal nerve on 3D double-echo steady-state with water excitation sequence.. AJNR Am J Neuroradiol 2015;36:1333–37, 10.3174/ajnr.A4288
  3. Zhang Z, Meng Q, Chen Y, et al. 3-T imaging of the cranial nerves using three-dimensional reversed FISP with diffusion-weighted MR sequence. J Magn Reson Imaging 2008;27:454–58, 10.1002/jmri.21009
  4. Fujii H, Fujita A, Kanazawa H, et al. Localization of parotid gland tumors in relation to the intraparotid facial nerve on 3D-double-echo steady-state with water excitation sequence. Paper presented at: 102nd Scientific Assembly & Annual Meeting of the Radiological Society of North America; November 27–December 2, 2016; Chicago, IL.

Read this article at AJNR.org …