Jason Allen
It has been apparent since the time of the early neuroanatomists that the white matter of the CNS was organized in predictable bundles. With the advent of neuroimaging, in particular, MRI, a number of these white matter tracts could be identified. However, the complexity of several of these tracts, particularly their branching and intersecting patterns, … more »
Joseph Helpern
Water molecules diffusing in the brain can be used to probe tissue microstructure noninvasively with diffusion MRI (dMRI). The microstructural distances to which dMRI is most sensitive are set by the typical distance a water molecule diffuses during the approximately 100 ms needed to acquire an individual dMRI signal. This distance of about 10 … more »
Els Fieremans
Andreana Benitez
Our research focuses on the study of degeneration in brain white matter, which consists primarily of myelinated axons that connect gray matter regions, using MRI. Although Alzheimer disease (AD) is typically considered a gray matter disease, postmortem studies have … more »
Jacobus F.A. Jansen
Notwithstanding recent advances in surgical and oncologic treatments, the overall survival rate of patients with head and neck squamous cell carcinoma (HNSCC) has unfortunately not improved considerably over recent years. A priori predictors of outcome are desperately needed to advance patient care; for example non-invasive imaging markers might have a … more »
Amir Paydar
Human embryology and development is indeed one of the most (if not the most) fascinating subjects in the field of biological sciences. Nevertheless, our scientific community still faces challenges in trying to understand the concepts that define the underlying mechanisms of embryology and tissue development. After all, it is a very complex subject … more »
Eytan Raz
Maxim Bester
Histopathological studies have shown that spinal cord WM and GM are affected by demyelination and neuronal loss in patients with MS. Advanced MRI techniques such as diffusion-weighted and diffusion tensor imaging (DWI and DTI) allow the detection and quantification of … more »
Jeffrey Berman
The auditory radiation is the gateway to the brain for sound sensation. However this functionally important tract is not easily delineated with traditional DTI tractography. Other sensory input pathways such as the somatosensory and optic radiations have been extensively studied with traditional DTI because they comprise relatively simple single-fiber architectures. The auditory radiation … more »