Edward D. Greenberg
Idiopathic intracranial hypertension (IIH), also referred to as pseudotumor cerebri, is a well known but poorly understood disease entity that presents neuroradiologists with both diagnostic and treatment challenges. The classic clinical presentation is that of an obese young woman, frequently African American, with headaches, nausea, vomiting, visual impairment, and possibly cranial nerve VI palsy. … more »
Ashley H. Aiken
Our manuscript is the first in the radiology literature to evaluate the incidence and morphology of cerebellar tonsillar ectopia (CTE) in patients with a clinical diagnosis of idiopathic intracranial hypertension (IIH). We first became interested in the appearance of the cerebellar tonsils as we witnessed the clinical dilemma the surgeons faced in patients … more »
Edzard Wiener
Jan Hoffmann
Headaches are one of the most common reasons for patients to seek medical advice. In our headache outpatient department we commonly attend patients suffering from idiopathic intracranial hypertension (IIH), which represents one of the main focus areas of our … more »
G. Michael Halmagyi
Geoffrey D. Parker
We chose this topic following the pioneering work of our colleague Dr. Ian Johnston, an eminent neurosurgeon who has struggled to unravel pseudotumor cerebri (PTC) for 40 years now.1 Our first success was in the late 1990s, … more »
David Pelz
Idiopathic intracranial hypertension (IIH) is a syndrome caused by raised intracranial CSF pressure (ICP) without an underlying mass lesion, hydrocephalus, or cerebral edema. Patients typically present with intractable headaches (90%), papilledema (89%), visual changes (62%), and pulsatile tinnitus (48%). In North American women, it has a prevalence of 15–19/100,000. If left untreated, it … more »
Our Search for Evidence of Impaired CSF Homeostasis in Obesity-Associated Idiopathic Intracranial Hypertension
Noam Alperin
The CSF system is a fascinating, elegant biomechanical environment important for a wide range of critical physiologic processes, from facilitating the cerebral circulation of the pulsatile blood flow in the confined space of the cranium to the accommodation of large hydrostatic changes … more »
Beyond Eyeballing the Eyeballs in Intracranial Hypertension
Noam Alperin
Deformation of the posterior sclera is a well-established imaging sign of intracranial hypertension (IH). In an excellent review article, Passi et al describe the appearance of the optic nerve (ON) and ocular regions on MRI in the presence of papilledema associated with increased intracranial pressure (ICP).1 They … more »
Anat Kesler
My main research area in neuro-ophthalmology is idiopathic intracranial hypertension (IIH) syndrome. In recent years, I have concentrated on advancing my research of this syndrome and have published papers in this field. IIH is a syndrome of increased intracranial pressure without an intracranial mass. When papilledema is present, neuroimaging is obtained before a lumbar … more »