Guest EditorCarlos Zamora
Susceptibility-weighted imaging (SWI) is a high-resolution, fully velocity-compensated gradient-echo MRI sequence that maximizes intrinsic contrast differences between tissues by virtue of their local magnetic properties. This technique exploits susceptibility information contained within phase acquisitions and merges such with magnitude data to generate a clinically usable set of images. Notably, the functional … more »
E. Mark Haacke
The development of susceptibility-weighted imaging (SWI) began in the mid-1990s, just following the advent of blood oxygen saturation imaging. Our group had been involved in the early brain/vein debate, that the veins played the critical role in visualizing information on brain function,1 not diffusion. We set out to demonstrate this and in … more »
Thangamadhan Bosemani
Our research team has focused on the clinical applications of advanced neuroimaging techniques, such as susceptibility-weighted imaging (SWI) in the evaluation of pediatric neurologic disorders. SWI provides useful functional information about blood oxygenation levels in intracranial vessels. In pediatric arterial ischemic stroke (PAIS), SWI focusing on venous drainage can provide noninvasive information about … more »
Yulin Ge
Over the last decade, susceptibility weighted imaging (SWI) has grown tremendously as a new clinical face in routine brain MRI in addition to T1- and T2-weighted imaging. It is particularly useful in detecting small intracranial hemorrhages and venous anomalies due to its increased sensitivity to higher susceptibility materials such as iron and deoxyhemoglobin 1. … more »
Zhicai Chen
JianZhong Sun
Intravenous thrombolysis with recombinant tissue plasminogen activator is a proved treatment for acute ischemic stroke within 4.5 hours of symptom onset. The foundation of intravenous thrombolysis for ischemic stroke involves reperfusion of the ischemic penumbra and salvage of threatened … more »