Vahe Zohrabian
Normal pressure hydrocephalus (NPH), first described by Hakim and Adams in 1965,1,2 is a potentially reversible syndrome characterized by cognitive impairment, gait disturbance, and urinary urgency or incontinence, associated with enlargement of the ventricular system and normal CSF pressure. Originally considered “idiopathic” and classically presenting in the seventh and eighth decades of life, today, … more »
Geir Ringstad
At our hospital, patients with idiopathic normal pressure hydrocephalus (iNPH) are selected for shunt surgery based on overnight intracranial pressure (ICP) monitoring, as 9 out of 10 patients with pulsatile ICP above threshold levels have proven to benefit from the treatment.1 Furthermore, the ICP test has high specificity for ruling out patients who would … more »
Johan Virhammar
Epidemiologic studies indicate that idiopathic normal pressure hydrocephalus (iNPH) is a much more common disease in the elderly population than previously believed.1 Even though iNPH is increasingly recognized, the number of shunt implantations performed is far lower than the occurrence of the disease. For decades, reliable tests that can aid in the diagnosis … more »
Shigeki Yamada
My mentor, Dr. Masatsune Ishikawa, who is one of the opinion leaders in the field of adult hydrocephalus, made me realize my interest in water related with the brain.
Idiopathic normal pressure hydrocephalus (NPH) is the most common type of hydrocephalus. We would like to emphasize that panventriculomegaly (eg, Evans index >0.3) is not … more »
Yoshiyuki Nishio
Wataru Narita
Idiopathic normal pressure hydrocephalus (iNPH) is a neurologic disorder clinically characterized by gait disturbance, cognitive impairment, and an overactive bladder. Ventriculomegaly has been considered a neuroimaging hallmark of iNPH, which reflects the compression of the brain parenchyma caused by … more »
John Huston
MR elastography (MRE) of the brain is a novel biomarker capable of measuring the stiffness of the brain noninvasively. MRE is a 3-step process whereby shear waves are introduced by a soft, pillowlike driver placed within a standard head coil. The 60-Hz vibration has been well tolerated in our practice and we have … more »