Alexandre Boutet
Evolution in neuroradiology, and indeed the wider radiology field, is in part dictated by novel diagnoses, therapies, and imaging techniques. The most frequently encountered indications and imaging modalities have changed drastically over the past decades. The expectations of radiology reports are also changing, with a trend toward the use of standardized reporting and quantitative … more »
Erik Middlebrooks
The globus pallidus externus (GPe) is an important node in the basal ganglia circuitry that has been shown to be dysfunctional in numerous disorders, such as Parkinson disease and dystonia. Despite this, there has been relatively little investigation of the GPe in the realm of neuromodulation, with far more focus on the more … more »
Jiachen Zhuo
I work with a group of researchers at the University of Maryland School of Medicine who have been at the forefront of MR imaging–guided focused ultrasound (MRgFUS) development to treat movement disorders including essential tremor, Parkinson disease, and neuropathic pain and develop other techniques including blood-brain barrier opening and neuromodulation. A key question … more »
Erik Middlebrooks
Parkinson disease is a relatively common and debilitating neurologic disorder. One of the most widely used indications for deep brain stimulation (DBS) worldwide has been in Parkinson disease, in which it has been shown to not only be highly effective in symptom control, but also allow the reduction of other medications that have … more »
Jeffrey Anderson
Functional MRI connectivity is an exciting technique that has redefined functional network neuroanatomy. Yet few clinical applications have emerged using this technique. One of the key limitations in using this approach in individual patients has been the inherent noise in the images, which limits the precision with which functional mapping targets can be … more »
Erik Middlebrooks
Dystonia is a debilitating condition for which deep brain stimulation (DBS) has been suggested as an effective and minimally invasive therapy; however, experience with DBS for dystonia has been mixed. One of the major barriers with dystonia DBS is the lack of immediate clinical biofeedback, such as that seen with Parkinson disease and … more »
Erik Middlebrooks
During the 21st century, our understanding of the human brain has exponentially grown, in part driven by the field of brain connectomics. Using this technology, we continue to understand more and more about normal and abnormal brain circuits that have greatly enhanced our understanding of many neurologic disorders. Through this framework, we have … more »